Figure 1: Constitutive 5-HT 2 receptor activity, but not residual 5-HT, causes spasms. Before injury, the spinal cord was densely innervated by 5-HT fibers along its whole length, particularly in the ...
The ancient biochemical 5-hydroxytryptamine—also known as 5-HT and serotonin—has been controlled through evolution to be used widely across the plant and animal kingdoms. 5-HT is used by mammals as a ...