Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery. Our immune system is armed with an array of defenses designed to detect and ...

New study uncovers how antibody combinations synergistically boost complement activation to combat drug-resistant Klebsiella pneumoniae infections. Study: Agnostic B cell selection approach identifies ...

Changes to serum proteins could be behind the debilitating condition known as long COVID. The findings, published in the journal Science, could pave the way for diagnosing and treating the disease.

Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath. As researchers have discovered, this is to some extent due to a part of our immune system called the complement ...

We are studying the role of the complement system in kidneys and brains during health and disease. Traditionally, major complement proteins were shown to be generated by the liver and are functional ...

An MUSC research team reports in Cells that the complement system, part of the body's natural immune defenses, is a key ...

A research team at the Medical University of South Carolina reports in Cells that the complement system, part of the body's ...

Most people infected with the SARS-CoV-2 virus recover after the acute illness. However, a significant proportion of infected individuals develop long-lasting symptoms with a wide range of ...