Drug metabolism is a central factor in drug discovery and development, impacting safety, pharmacokinetics, and pharmacodynamics. Research into drugs’ in vitro metabolism in human and animal tissues ...

Study reveals the potential of gut bacteria-derived metabolites, such as 4-hydroxyindole, to revolutionize endometriosis diagnosis and treatment, paving the way for microbiota-based therapies. Study: ...

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break ...