A key protein involved in fat metabolism has been found to do more than scientists once thought. Instead of just releasing fat, it helps maintain healthy fat tissue and balance in the body. When it’s ...

Adipose tissue is an underappreciated and misunderstood organ. Capable of more than doubling in mass and then returning to baseline, 1 white adipose tissue (WAT) continues to play an essential role in ...

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders. A research team led by Professor Jong Kyoung Kim from the Department of Life Sciences ...

As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major ...

Transcriptomic phenotyping offers mechanistic insight into adipocyte biology and metabolic disease. A signature of adipocyte ...

Two studies reported separately by researchers at Columbia Engineering and Columbia University Irving Medical Center (CUIMC) demonstrate a new approach to obesity treatment that uses a positively ...

Uncovering the mystery of why individuals born with mutations in the gene that encodes HSL—the cytosolic enzyme that releases energy from fat—lose fat instead of gaining it, Dominique Langin, PhD, ...

Let us leave aside our obsession with COVID and consider two more significant health problems that have long plagued us, obesity and cardiometabolic disease resulting in hypertension, diabetes, and ...

Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored ...