Amyloid precursor protein (APP) is a type I transmembrane glycoprotein that undergoes complex routing through the secretory and endocytic pathways of neurons and non-neuronal cells. Proteolytic ...

(A, B) ALP staining and activity detection were performed after treating cells with APPswe or BMP2 for 5 days or 7 days. (C, D) ARS staining and semiquantitative analysis were used to detect calcium ...

At the end of last month, a scientific journal pulled a research paper on Alzheimer’s disease. The retraction came from Neurobiology of Aging, which removed a 2011 paper claiming to show that a ...

Beta-amyloid plaques are considered a hallmark of Alzheimer’s disease, but they’re not the sole cause of the disease and its symptoms. Alzheimer’s is a complicated disease that experts are still ...