An antigen is any substance that can trigger an immune response in the body. Antigens are typically proteins or polysaccharides that are recognized as foreign or potentially harmful by the immune ...

Chimeric antigen receptor T-cell (CAR-T) therapies have emerged as a revolutionary approach in the field of hematological malignancies, offering unprecedented clinical efficacy when patients have ...

To activate T cells, DCs take up, process, and present antigens as part of major histocompatibility complexes (MHCs) that interact with T cell recep­tors. Therefore, Curtis and her team set out to ...

The terms “process-specific” and “generic” are commonly used in scientific publications and regulatory guidelines in reference to host cell protein (HCP) analysis of recombinant biopharmaceuticals.

Tumor immunotherapies, especially those leveraging T cells to identify and eliminate cancer cells, represent a major breakthrough in cancer treatment. However, many tumor-associated antigens are too ...

Scientists designed vaccines to treat HPV-positive head and neck cancer. All vaccines had the same ingredients but different, ...

An international research team with strong participation from DTU has developed a new biotechnological platform that makes it possible to test and understand advanced cancer treatments much faster and ...