CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice. Their work establishes a next-generation gene-editing tool that enhances genetic ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

AI‑driven protein design creates potent anti‑CRISPR inhibitors that block Cas13 activity, offering a new potential tool for safer, more controlled gene editing.

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism.

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

This figure illustrates the evolution of CRISPR technology from 1987 to 2019, presented in a horizontal timeline format and categorized into four generations, each denoted by a distinct color: The ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...