Bufadienolides, a class of cardiotonic steroids primarily isolated from toad venom, have emerged as potent agents in the field of cancer therapeutics. Their bioactivity is largely attributed to their ...

Capsaicin, the bioactive compound responsible for the characteristic spiciness of chilli peppers, has attracted considerable attention for its anticancer properties. In various cancer cell types, ...

The Bcl-2 family of proteins, known for their crucial role in regulating apoptosis, present an intriguing opportunity for advancing cancer immunotherapy. Recent studies have highlighted their ...

Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company focused on developing innovative therapeutics, today announced that the China National Intellectual Property ...

The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...

Colorectal cancer is one of the most prevalent tumors and a leading cause of cancer-related mortality. Despite advances ...

Pancreatic cancer is notoriously hard to treat, often resisting therapies that target its most common mutations. Researchers have now uncovered a hidden three-part loop that fuels tumor growth, ...

Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...

The China National Intellectual Property Administration approved the patent covering Hoth’s HT-KIT technology, which is designed to induce apoptosis (programmed cell death) in cancer cells by ...

Even with breakthroughs, treatment for advanced squamous cell carcinoma is more complex. Patients often need more than one treatment. Many patients with this advanced cancer are cared for by a team of ...