A caffeine-triggered switch that turns CRISPR gene editing on and off inside cells could one day improve cancer therapy.

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new computational approach designed to ...

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

In the early 20th century, Paul Ehrlich coined the term “magic bullet” to describe a therapy that could selectively eliminate disease without harming healthy tissues. A century later, Ehrlich's vision ...

The first study on deuterium-depleted water (DDW) concluded that a higher D/H ratio inside cells can trigger cell division. This was supported by lab experiments showing that lowering deuterium levels ...

Gene expression testing, such as Oncotype DX, aids in chemotherapy decisions for hormone receptor-positive breast cancer, though challenges exist for premenopausal patients with scores under 25.

Researchers at The University of Texas MD Anderson Cancer Center have developed a new computational approach designed to ...