A surprising new function of essential hearing proteins may explain why some genetic mutations and common antibiotics lead to permanent deafness.
Researchers discover that hearing-essential proteins (TMC1/TMC2) also regulate cell membranes, and their malfunction is a primary cause of permanent hearing loss.
Scientists link TMC protein membrane disruption to hearing loss, showing how mutations, drugs and noise trigger hair cell death and deafness.
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Proteins long known to be essential for hearing have been hiding a talent: they also act as gatekeepers that shuffle fatty molecules across cell membranes. When this newly discovered function goes ...
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