A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

A study shows epigenetic proteins regulate genes through diverse dynamic patterns, not simple on-off control, with each ...

Scientists are uncovering the intricate ways our genes turn on and off, shaping everything from butterfly wings to cancer therapies. Advances in single-cell analysis, epigenetic mapping, and AI-driven ...

Researchers have shown that different epigenome proteins can produce distinct gene expression patterns from the same gene, offering new insights into genetic regulation. The findings could help ...

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with ...

California-based startup Fermeate has raised $2 million in seed funding to scale its optogenetics platform, which uses light ...

A collaborative effort has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...