A new AI tool reveals how tangled DNA knots impact health and disease, offering insights for drug discovery and genetic ...

By creating a more true-to-life representation of DNA's environment, researchers have discovered that strand separation may take more mechanical force than the field previously believed.

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation—the essential process a "resting" double helix ...

DNA doesn’t knot under stress. A new study finds it coils into plectonemes, reshaping models of genome mechanics. For decades ...

Unexpected slowdowns or spikes in this signal were often interpreted as knots in DNA. But now, a new study published Aug. 12 ...

They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. This is the finding of a study led by Ulrich ...