CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...
The alternative text for this image may have been generated using AI. The natural prevalence of R-loops and G4s at telomeres and promoters can facilitate genomic maintenance of these features. At ...
In the early 2000s, Tawfik presented his ‘New View’ on enzyme evolution, highlighting the role of conformational plasticity in expanding the functional diversity of limited repertoires of sequences.
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