As cell and gene therapy leaders gathered in Maryland to discuss accelerating clinical trials in children, one “cutting edge” ...

Researchers have mapped the 3D organization of genetic material of key developmental stages of human retinal formation, using intricate models of a retina grown in the lab. The findings lay a ...

In a new study published in Genes & Development, research led by Dr. Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for ...

Weill Cornell Medicine researchers have found that temporarily disabling a protein complex that organizes DNA into loops ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...

The human brain's remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities. Disruptions in this process may explain certain ...

Cold Spring Harbor, NY – Cold Spring Harbor Laboratory Press (CSHL Press) has announced the appointment of new editorial leadership at its renowned journal, Genes & Development. Professor Andrew ...

Researchers have discovered that blocking both genes brings about a significant reduction in tumor size. The study reveals important differences between tumors in male and female Drosophila and how ...

“A central question has been: How do thousands of genes work together in an embryo, and how is their activity linked to the movement of cells?” says first author Yinan Wan. To answer this question, ...

Embryonic development doesn't occur by magic; it occurs by predetermined genetic steps leading to production of transcriptional molecules. This process is addressed by two Faculty of 1000-featured ...

To generate successful gene therapies that are capable of delivering nucleic acids to specific cells and tissues, scientists must carefully design their products. They can employ either recombinant ...