Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the ...

A so-called "molecular chaperone", the protein Hsp70, carries out more functions in the maturation of proteins than previously thought. As the researchers have discovered, Hsp70 not only acts as a ...

At the inner mitochondrial membrane, a high energy electron is passed along an electron transport chain. The energy released pumps hydrogen out of the matrix space. The gradient created by this drives ...

ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. Researchers have isolated the machines from four fungal species, compared their stabilities ...

The mitochondrial ATP synthase is energy-converting macromolecular machine that uses the electrochemical potential across the bioenergetic membrane called cristae. This potential is maintained via a ...

The c-ring is formed by two staggered, concentric rings of 15 helices, resulting in a clockwise vorticity when viewed from the cytoplasm. Both helices of one c subunit are connected by a loop on the ...

Mitochondrial ATP synthases form dimers, which assemble into long ribbons at the rims of the inner membrane cristae. We reconstituted detergent-purified mitochondrial ATP synthase dimers from the ...