Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

The open-label, single-arm study enrolled 23 adult patients undergoing their first kidney transplant from either living or ...

Baseline stool metagenomic profiling in CheckMate 915 linked specific bacterial taxa with recurrence-free survival after ...

Experts at Cincinnati Children's report proof-of-concept results that may sharply reduce the risk of a lethal side effect that has negatively impacted the use of revolutionary cancer immunotherapies ...

View all available purchase options and get full access to this article. Supported by the National Cancer Institute at the National Institutes of Health as a Cancer Center Support grant to the ...

When immune checkpoint inhibitors are used in cancer treatment, in some cases it can lead to severe inflammation and damage to heart tissue. Histology images of mouse heart tissue illustrate the ...

Positioned to Enhance Efficacy of Checkpoint Inhibitors and Next-Generation Oncology Modalities Across Solid Tumors ATLANTA, ...

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar ...

The timing of myocarditis onset during immunotherapy treatment for cancer may predict how likely a person is to die of the condition, according to retrospective study results.Patients who developed my ...