Brain tissue analysis of an animal model has revealed the potential role of immune system dysfunction in the onset and progression of Alzheimer's disease (AD). Published April 15, 2025 in the Journal ...

Eighty percent of patients with autoimmune diseases are female. These diseases are one of the top 10 leading causes of death for women under 65, and cases are increasing annually worldwide. There is ...

Among modern cancer therapies, immune checkpoint inhibitors (ICI) are among the most successful treatment methods. These ...

Neurodegenerative diseases, traditionally viewed as driven by neuronal decline, are increasingly recognized to involve significant immune dysfunction within and outside the central nervous system (CNS ...

The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

Engineered antigen-presenting extracellular vesicles (AP-EVs) deliver peptide-MHCII, IL-2, and TGF-β to naïve antigen-specific CD4⁺ T cells, driving their differentiation into Foxp3⁺ regulatory T ...

There are at least 70 documented autoimmune diseases [36] and the prevalence of autoimmune disease is rapidly rising worldwide, for reasons not completely understood. [37] Although the disorders share ...

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

High cannabis use is associated with worse lung function, respiratory symptoms, and airway immune changes, highlighting ...