Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or ...

High-resolution microscopic images of T cells that have been engineered with TGF-beta SNIPRs (shown in red) as they bind to TGF-beta (shown in green). The SNIPRs activate once the receptors fold into ...

Florida Atlantic University has received a $2.4 million grant from the National Institutes of Health to investigate how an immune-related receptor in neurons plays a fundamental role in brain function ...

GABA receptors, long recognised principally for their role in modulating neuronal excitability within the central nervous system, are now emerging as pivotal regulators of immune function. These ...

Researchers engineered immune cells that protect insulin-producing cell transplants, bringing scientists closer to a cure for type 1 diabetes.

The human immune system is based on cells that communicate with each other via signaling molecules known as cytokines and chemokines. One of these signaling molecules is the protein MIF (macrophage ...

Researchers are developing a two-part therapy for type 1 diabetes: lab-made insulin-producing cells paired with ...

Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor ...