A novel indwelling subcutaneous intrathecal catheter circumvented the complex spine anatomy of patients with spinal muscular atrophy (SMA), a challenge when giving nusinersen via intrathecal injection ...

Credit: FDA. The FDA has received reports of tranexamic acid injection being erroneously administered intrathecally in the perioperative setting instead of the intended intrathecal anesthetic (eg, ...

Glycine, taurine, or muscimol was injected with bicuculline into the cistern magna or the lumbar subarachnoidal space in ICR mice. The effects on bicuculline-induced allodynia in a touch-evoked ...

THE neurologic manifestations of Central-nervous-system involvement in acute leukemia have been very well described. 1–7 Although involvement of the brain is not rare 7,8 greater emphasis has been ...

Heitor Medeiros, MD, and A. Sassan Sabouri, MD, of the Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital, are the lead and corresponding authors, respectively ...

In a recent study published in Nanomedicine: Nanotechnology, Biology and Medicine, researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous ...

A 49 year old woman was diagnosed with Philadelphia negative B-acute lymphoblastic leukemia (B-ALL) and subsequently started on induction chemotherapy with systemic cyclophosphamide, doxorubicin, ...

The choice of which drug or combination of drugs, via what route, and in what manner remains a concern for the clinician. In choosing the dose and volume of local anesthetic for epidural labor ...

Heitor Medeiros, MD, and A. Sassan Sabouri, MD, of the Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital, are the lead and corresponding authors, respectively ...

Recent studies investigating the management of analgesia in childbirth have demonstrated that pain relief can be started early in labor with no negative consequences. Also of particular importance are ...