Despite the ongoing increase in the number of vaccinated individuals, testing still has an important role to play in the global response to the COVID-19 pandemic. PCR-based testing has so far been the ...

Fundamentals of LC-MS method development and easier approaches,Overview of method validation and transferStandard operating procedures for LC-MS modules, and troubleshooting strategies. Theory of ...

Biomarkers play an important role in drug development and help in the identification of disease-causing proteins found in blood, urine, body fluids, and tissue samples. The combination of liquid ...

To improve and validate analytical methods based on HPLC and liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) for the quantitative measurement of ...

The UPLC system was configured with an Acquity Premier Oligonucleotide C18 column (1.7 µm, 2.1 × 50 mm). The aqueous and ...

LC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over more commonly used analytical techniques. However, ...

A recent study employed high-throughput liquid chromatography-mass spectrometry (LC-MS) to perform comprehensive metabolic profiling on plasma samples from nearly 4,000 women. By leveraging the ...

Drs Dawn Dufield and Dominic Warrino, KCAS Bioanalytical and Biomarker Services, share expertise on using Hybrid LC-MS versus LBA for bioanalytical analysis. Selecting the right bioanalytical method ...

MG is present in solution under physiological conditions in three forms: the unhydrated form CH 3 COCHO, the monohydrate CH 3 COCH(OH 2) and the dihydrate CH 3 C(OH) 2 CH(OH 2), which at equilibrium ...