Fibroblastic reticular cells (FRCs) are heterogeneous stromal cells. Subsets of FRCs include: T cell zone reticular cells that produce interleukin-7 (IL-7) to support naive T cells; resident and ...

However, researchers now suggest that lymph nodes are not essential in the mouse in marshalling T-cells (a main immune foot soldier) to respond to a breach of the skin barrier. This result is both ...

Researchers report a new way to turn off the harmful immune attack that occurs during autoimmune diseases such as multiple sclerosis (MS), while keeping healthy functions of the immune system intact.

Stromal cells in the subcapsular sinus of the lymph node 'decide' which cells and molecules are allowed access to the deeper parenchyma. The glycoprotein PLVAP is a crucial component of this selector ...

A lymph node biopsy is a test that checks for disease in your lymph nodes. Lymph nodes are small, oval-shaped organs located in different parts of your body. They’re found close to internal organs ...

Lymph nodes are a key part of the human immune system, whose primary function is to combat infections. The effectiveness of vaccines is based on their ability to trigger events in lymph nodes that ...

New research has shown why preserving lymph nodes, often removed near tumours to prevent cancer spread, could improve patient outcomes and make immunotherapies more effective. A team of researchers, ...

A recent paper in Nature Biomedical Engineering, by Dr. David J. Mooney demonstrated how a new vaccine can enhance and maintain lymph node function to boost immunity against cancer in mice. Mooney, a ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...