Although many effective small molecule drugs are known to work by interacting with the genome, their underlying mechanism often remains unclear. Gaining an understanding of where and how small ...

In a paper published in Science magazine, a group of scientists introduce the Connectivity Map (C-Map). It's an online database connecting the genetic signatures of diseases to those of available ...

As co-founder and CEO of Pepper Bio, Jon leads one of the world's first transomics drug discovery companies. Road trips can vary greatly depending on a driver’s goal: Do you want to take the scenic ...

When you take a drug, where in your body does it actually go? For most medications, scientists can make only educated guesses about the answer to this question. Traditional methods can measure the ...

Drug overdoses are one of the leading causes of injury death in adults, and they have risen in the United States over the past several decades. Thousands of pounds of narcotics enter the U.S. every ...

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential effective ...