New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying ...

“This is a paradigm shift,” says Donn Van Deren, PhD, postdoctoral research fellow at the University of Pennsylvania, who conducted the research while working in human genetics at the University of ...

Alzheimer’s disease has long looked like a slow-motion wildfire, starting in one part of the brain and then advancing along ...

New research in The American Journal of Pathology has identified neuroinflammation, driven by microglia (immune cells), as a ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed ...

Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord from age-related damage.

Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord ...

Immune-regulating brain cells known as microglia are known to play a role in the progression of Alzheimer’s disease (AD). Investigators at Brigham and Women’s Hospital studying the genetics of ...

In diseases driven by dysfunctional microglia, could replacing them with healthy versions prevent, or even reverse, pathology? Yes, suggest two papers in the June 18 Neuron. Both describe how mice ...