A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...

Some serious brain disorders begin with symptoms that are easy to misinterpret. A person may become confused, forgetful or ...

New OHSU study maps antibody "hot spots" behind anti‑NMDAR encephalitis. Could change diagnosis and treatment.

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

A relatively new class of autoimmune diseases that affect the brain is making psychiatrists rethink some diagnoses.

BUFFALO, N.Y. — When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and ...

Scientists have identified a promising target for treatment of a devastating autoimmune disease affecting the brain.

The links between neurons are crucial to the brain, and brain cells can reorganize the way they are linked together in a phenomenon known as neuroplasticity. This process is ongoing during a lifetime, ...

A new study suggests a potential molecular strategy for treating fragile X syndrome, an inherited neurodevelopmental disorder that causes autism spectrum disorder and intellectual disability. This ...

The images showed that nearly all the antibodies bind to a single domain of the receptor, providing a viable target for novel therapeutics.

Neurons generated from stem cells (from skin fibroblasts) of a patient with sporadic Alzheimer’s disease. Visualized with a specific green fluorescent marker. Nuclei are shown in blue. Researchers ...