Innate immune system cells control megakaryopoiesis They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis). This ...

Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of ...

In a recent study under review in the Journal of Hematology & Oncology journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute ...

Immune thrombocytopenia (ITP) is a chronic autoimmune disorder associated with platelet destruction and increased bleeding risk, substantial economic burden, and impairment of health-related quality ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor ...

Neonatal alloimmune thrombocytopenia (NAIT) is a disorder that affects pregnant people and their fetuses. It occurs when the birthing parent’s immune system produces antibodies that attack and destroy ...

They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis). This decisive process is regulated by the innate immune system ...