We set out to develop general methods for designing proteins that bind peptides in helical conformations. To fully leverage recent advances in protein design, we explored both parametric and deep ...

PepMLM, a protein language model fine-tuned on protein–peptide data, can generate potent, target-specific linear peptides capable of binding to and degrading proteins ranging from cancer receptors to ...

An MIT-developed AI model has designed dozens of lab-confirmed protein binders for targets long considered out of reach, offering a new tool for drug discovery and ...

For the field of drug development, hitting the right target with atomic precision to achieve therapeutic effect remains the core challenge. While traditional R&D pipelines are dependent on ...