A group of international researchers reports the availability of a new “map”’ of every gene, protein, and metabolic pathway required for a cell to efficiently secrete recombinant proteins. The team, ...

Gram-negative bacteria deploy a suite of dedicated secretion pathways to traverse their dual-membrane envelope and deliver proteins critical for nutrient acquisition, environmental adaptation and ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

snoRNAs were thought simply to guide chemical modifications to rRNAs, but a new technique has revealed a suite of potential functions in protein secretion. A recent research effort from the University ...

Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell.

UAB researchers have identified Tomosyn 2 as a key protein that balances insulin secretion and pancreatic beta cell growth, ...

Uncontrolled secretion of extracellular matrix (ECM) proteins such as collagen can lead to excessive scarring and fibrosis, and compromise tissue function. Researchers at the Center for Genomic ...

In type 2 diabetes, the body's ability to release insulin is impaired, which leads to high blood glucose levels. Research led by Lund University shows how the levels of a particular protein are ...