The ability of RPA to outcompete POT1–TPP1 raises the question of how ATR activation is suppressed in cell extracts. Purified RPA bound to ssTEL and mutated telomeric repeats (ssMUT) efficiently (Fig.
Activation-induced cytidine deaminase (AID) is a single-stranded (ss) DNA deaminase required for somatic hypermutation (SHM) and class switch recombination of immunoglobulin genes. Class switch ...
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