Scientists at the University of Birmingham and the Francis Crick Institute have discovered a new way in which cancer cells repair double-stranded breaks in DNA. The findings were published in a paper ...

Scientists have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair ...

A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...

Normally, DNA breaks are introduced at the beginning of meiotic recombination. However, such DNA breaks are a threat to a cell and must be repaired immediately. The newly identified C19ORF57 gene ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...

A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

Circulating tumor DNA (ctDNA) mutations may predict treatment response in extensive-stage small cell lung cancer (ES-SCLC) treated with talazoparib and temozolomide (TMZ). This is an ASCO Meeting ...