The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...

A. Fluorescent immunostaining of PDGFRα, showing mesenchymal progenitors, laminin surrounding skeletal muscle, and AR. Arrows indicate mesenchymal progenitors expressing AR, arrowheads indicate ...

Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle ...

A new study has observed differences in the shape, structure and mechanical properties of nuclei in trained and untrained individuals, potentially helping to explain the anti-aging effects of exercise ...

Researchers identified a critical AMPK phosphorylation site that regulates mitochondria, muscle contraction, and sugar ...

Neuromuscular disorders can be caused by hereditary or acquired genetic mutations, impairing the function of skeletal muscles: those under voluntary control. These diseases cause muscles to weaken and ...

Study uncovers a polyphenol's mechanism in enhancing mitochondrial calcium uptake and muscle bioenergetics during aging. Study: Mitochondrial calcium uptake declines during aging and is directly ...

Mice retained normal muscle function and health even though their NAD+ levels were reduced by 85%, according to new research from the University of Copenhagen. Given that NAD levels drop by only up to ...

Girish Melkani, Ph.D., recently promoted to professor in the Department of Pathology, has been named the latest recipient of the school’s Featured Discovery award. This recognition celebrates notable ...

“Instead of inserting the corrected piece of information, we used CRISPR to cut DNA in two strategic places,” study coauthor Dwi Kemaladewi, a research fellow at the Hospital for Sick Children (Sick ...