Parkinson's disease (PD) is a debilitating and progressive neurodegenerative disorder caused by the loss of ...

This perspective argues that Parkinson’s disease may involve functional iron deficiency, where bioavailable iron is limited despite normal or elevated total iron in the brain. The authors propose that ...

Two proteins found on the surface of motor neurons in the brain may be essential in the progression of Parkinson's disease, ...

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region ...

You won’t get very far without dopamine. That is the problem at the heart of Parkinson’s disease; the death of dopamine-producing cells eventually leaves many patients unable to walk. Too much ...

To answer this question, the researchers, led by neuroscientist and study coauthor Pei Zhang at Huazhong University of Science and Technology, took a mouse model of pre-symptomatic Parkinson’s disease ...