A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

Immune checkpoint inhibitor (ICI) therapy before surgery for hepatocellular carcinoma (HCC) may produce major pathological ...

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

TLSs are highly organized structures that typically appear as clusters of B-cells containing FDCs. These clusters are then surrounded by T-cells and HEVs as shown schematically in Figure 1. We ...

Researchers have identified how to encourage tumors to build their own immune hubs—structures that look and function like lymph nodes—deep in the middle of cancer. Such immune hubs, known as tertiary ...

A team led by surgeon-scientist Dr. Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures. Therapeutically targeting this pathway could ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

REZILIENT3: Phase 3 study of zipalertinib plus chemotherapy in patients with previously untreated, advanced nonsquamous non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

Discover how specialized cells form immune-boosting niches in lung tumors, unlocking new strategies to enhance cancer treatments and improve outcomes. Study: Fibroblastic reticular cells generate ...