Rare diseases, defined by FDA as “a disease or condition that affects less than 200,000 people in the United States” (1), may ...

Researchers at Utah State University have reported a previously unrecognised CRISPR immune response in which a bacterial ...

A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are ...

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of ...

The new findings strengthen the "RNA world" hypothesis that describes how the first life on Earth could have used RNA instead ...

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation, which ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Transfer RNA, more commonly referred to as tRNA, is well known for its key role in translating genetic material into protein. Recent discoveries about fragments of tRNA, which scientists had ...

IRE1α-driven production of 5’-tRH-Gly GCC during ER stress, aiding cellular adaptation in various eukaryotic organisms, ranging from yeast to humans To fill this knowledge gap, a group of researchers ...

In 1965, Cornell biochemist Robert Holley deciphered the 77 nucleotide sequence of transfer RNA. Three years later, Holley was awarded the Nobel Prize for this work, but already the race to determine ...

Initially dismissed as a wealthy and frivolous socialite, Charles Swann in Marcel Proust’s “In Search of Lost Time” eventually transforms from a minor figure to an important one. Were biology a novel, ...