The immune system responds to an infection by producing antibodies that recognize and bind to the cell surface of the pathogen, thus marking it as an intruder and triggering an immune response. For ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Using cryo-electron microscopy, researchers have analyzed the structure of trypanosomes parasites in details and revealed one of their potential weak points, which has remained undetected until now.

Trypanosome parasites transmitted by tsetse flies cause devastating diseases in humans and livestock. Different subspecies infect different hosts: Trypanosoma brucei brucei infects cattle but is ...

Researchers from Sebastian Zoll’s group at IOCB Prague determined the first cryo-EM structures of a surface receptor of the human-infective parasite Trypanosoma brucei gambiense in complex with human ...

Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes, a study shows. A parasite which has devastating impacts ...

Single specimens of the vermicular pathogens causing sleeping sickness swim inside the gut of the tsetse fly between blood cells which the fly has ingested from an infected mammal. This is where they ...

Australian trypanosomes are protozoan parasites that infect a diverse range of native wildlife, from marsupials to monotremes, with significant implications for conservation and biosecurity. Recent ...

Caught in the act! Researchers from the University of Bristol have observed mating for the first time in the microbes responsible for African sleeping sickness. This tropical disease is caused by ...

Trypanosome parasites transmitted by tsetse flies cause devastating diseases in humans and livestock. Different subspecies infect different hosts: Trypanosoma brucei brucei infects cattle but is ...