Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes. These two-dimensional cultures distort cell behavior, limiting ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and the molecular events within them are dynamic, and developmental processes, ...

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one ...

Nucleons, which include protons and neutrons, are the composite particles that make up atomic nuclei. While these particles have been widely studied in the past, their internal structure has not yet ...

Scientists have crossed a startling new frontier in bioengineering: they can now fabricate intricate three-dimensional objects inside living cells. Instead of sculpting tissue from the outside, they ...

The design of synthetic developmental programs for multicellular mammalian systems is a cornerstone of synthetic biology. The programs hinge on the construction of gene regulatory circuits that ...

The cochlea is the spiral-shaped structure within the inner ear responsible for our sense of hearing. To fully understand hearing functions and open the door to new hearing loss treatments, scientists ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...