Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...

A pragmatic cluster-randomized trial across 8 CHC sites (Boston and Los Angeles) enrolled 5127 adults aged 45–75 years overdue for screening, randomizing clinics to FIT versus FIT-DNA outreach.

Introduction Gestational diabetes mellitus (GDM) is associated with a high risk of adverse perinatal outcomes. We evaluated ...

Impact of a collaborative care-based symptom intervention model on chemotherapy adherence in patients with breast cancer. Electronic patient-reported outcomes with vital sign monitoring versus usual ...

Old Dog, New Tricks: Oxybutynin for the Treatment of Androgen Deprivation Therapy–Related Vasomotor Symptoms We conducted a population-based cluster-randomized clinical trial (Genetic Information and ...

For decades, a diagnosis of metastatic pancreatic cancer has carried one of the shortest survival timelines in oncology.

Background A regional trial indicated that implementing at-risk asthma registers in primary care could reduce hospital ...

Multipronged education and feedback intervention for clinics did not have intended results ...

Patient- and physician-facing interventions together doubled the reductions in PPI use ...

Delivery of the program needs rethinking because only about half of patients opt to use digital weight management.