A baby girl presented with symptomatic sickle cell disease exacerbated by mild hypoxemia, despite a newborn-screening diagnosis of sickle cell trait. DNA sequencing of the β globin gene revealed that ...

The evaluation of new drugs designed to treat specific anemias should include a thorough understanding of underlying pathophysiology, with a focus on enhancing oxygen transport. In this concise review ...

Red-blooded genealogists take note: The discovery in microbes of two oxygen-packing proteins, the earliest known ancestors to hemoglobin, brings scientists closer to identifying the earliest life ...

Researchers have discovered crucial information about the protein transporter of oxygen, which opens up the possibility to optimize its function by introducing modifications. The transport of oxygen ...

How proteins evolved the ability to form complexes made up of multiple subunits—and what functions this new structure enabled in early multimeric proteins—isn’t well understood. To better understand ...

ARLINGTON, Va.– Red-blooded genealogists take note: The discovery in microbes of two oxygen-packing proteins, the earliest known ancestors to hemoglobin, brings scientists closer to identifying the ...