How to Compare Two Excel Spreadsheets & Highlight What Is Missing. Comparing two spreadsheets using an automated tool eliminates the tedious task of manually analyzing cells for differences.

How to compare columns in Microsoft Excel As stated, we can use the Excel VLOOKUP function to find and match different data or find differences in two columns.

Microsoft Excel comes with a lot of built-in functionality that doesn't restrict you to comparing data in two columns using only one method.