New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death. Cancer cells that are resistant to anticancer drugs are known to be ...

Enzymes are proteins that catalyze chemical reactions in living organisms. They are widely applied in industries such as food ...

Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...

This article describes a simple method to determine the optimum pH for the activity of one enzyme in a coupled enzyme assay. Decoupling of the two-step reaction is achieved by heat denaturing the ...

Thermo Fisher Scientific Inc. TMO introduced the first automated discrete analyzers intended for enzyme assay applications -- the Thermo Scientific Gallery Enzyme Master and Thermo Scientific Gallery ...

During the last 50 years, an abundance of data has been gathered on the function of lipids as a source of energy, as building blocks, and as signaling molecules in living systems. Lipid-signaling ...

Nagoya University researchers have developed the SMART assay, a platform that screens enzymes at the single-molecule level, ...

Understanding how drug discovery screening cascades are constructed and optimized is essential for minimizing false positives ...

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