Q: My daughter, who is 14-years-old, was diagnosed with localized scleroderma about three years ago, and I am finding out that not much is known on this disease. Could you tell be about it? Does ...

Localized Scleroderma usually affects the skin and rarely spreads elsewhere, while Systematic Scleroderma can affect other organs of the body besides the skin. What are symptoms of Scleroderma?

Although the cause of localized scleroderma is unknown, an autoimmune mechanism is suspected. We describe two patients with localized scleroderma treated with topical tacrolimus, an ...

FCX-013 is Fibrocell’s clinical stage gene therapy candidate for the treatment of moderate to severe localized scleroderma.

Localized scleroderma is relatively mild, and is usually found on a few places of the skin or muscles. The internal organs are not usually affected and people affected with localized scleroderma ...

Localized scleroderma is a rare connective tissue disorder characterized by hardening and thickening of the skin due to increased collagen density. A quarter of patients affected also experience ...

Fibrocell seeks US FDA approval for gene therapy candidate, FCX-013 to treat moderate to severe localized scleroderma ...

However, the National Scleroderma Foundation states that an estimated 300,000 Americans have the disease. There are two major forms of Scleroderma: localized scleroderma and systemic scleroderma.

Bob Saget served on the board of the Scleroderma Research Foundation. His sister died of the disease at 47.

The autoantibodies anti-POLR3 and monospecific anti-Ro52 were associated with increased cancer risk, while anti-centromere and anti-U1RNP were tied to reduced risk.

Bob Saget was a tireless activist for the Scleroderma Research Foundation, inspired by the death of his sister, Gay ...

Two years before his death, Bob Saget quietly offered his support to a family whose 9-year-old daughter is suffering from Scleroderma, the same disease that took the life of his sister in 1994.