When some factors are harder to vary than others, a split plot design can be efficient.

PROC MIXED can fit a variety of mixed models. One of the most common mixed models is the split-plot design. The split-plot design involves two experimental factors, A and B. Levels of A are randomly ...

Using a split-plot design (SPD) structure reduces the number of times that these hard-to-change factors are reset during the experiment. A class of second-order response surface SPDs has been proposed ...

The resulting designs allow for a more powerful statistical inference than traditional optimal designs. In our algorithm for generating optimal blocked and split-plot designs, we implement efficient ...