The current role, limitations, challenges and prospects for protein structure modeling (using information about genes and genomes) are discussed in the context of structural genomics.

Homology modeling aims to build three-dimensional protein structure models using experimentally determined structures of related family members as templates. SWISS-MODEL workspace is an integrated ...

Protein structure modeling technology helps in the identification of potential binding sites, optimizing drug- target interactions, and predicting drug efficacy. Additionally, protein structure ...

Deep learning, 3D technology to improve structure modeling, create better drugs Date: January 10, 2020 Source: Purdue University Summary: Researchers have designed a novel approach to use deep ...

We study the properties of a three-step approach to estimating the parameters of a latent structure model for categorical data and propose a simple correction for a common source of bias. Such models ...

Chemists have developed a generative AI model that can make it much easier to determine the structures of powdered crystal materials. The prediction model could help researchers characterize ...

A Framework for Modeling Organizational Structure. An organizational structure helps a company ease the decision-making process, specifying things like who reports to whom, who makes final ...

To evaluate a protein docking model, DOVE scans the protein–protein interface of the model with a 3D voxel and considers atomic interaction types and their energetic contributions as input features ...

Deep learning, 3D technology to improve structure modeling for protein interactions, create better drugs DOVE, created by Purdue researchers, captures structural and energetic features of the ...