NEW YORK, Dec. 11, 2025 (GLOBE NEWSWIRE) -- Applied Therapeutics, Inc. (Nasdaq: APLT; “Applied”), a clinical-stage biopharmaceutical company dedicated to creating transformative treatments for rare ...

On Monday, Applied Digital announced its intention to conduct a private offering to raise $2.35 billion in senior secured notes due in 2030, the proceeds of which will be used to help fund ...

Buzzy autonomous vehicle software company Applied Intuition has closed a $600 million Series F and tender offer, pushing its valuation up to $15 billion. The round was co-led by BlackRock-managed ...

Chemists have developed an efficient skeletal editing method for frequently used heteroaromatic structures. The technique could serve as a means to chemically modify biologically active compounds.

Stable distributions are well-known for their desirable properties and can effectively fit data with heavy tail. However, due to the lack of an explicit probability density function and finite second ...

Purpose: Bayesian approaches may improve the efficiency of trials and accelerate decision-making, but reluctance to depart from traditional frequentist statistics may limit their use. Because oncology ...

Bayesian methods for inference and prediction have become widespread in the social sciences (and beyond). Over the last decades, applied Bayesian modeling has evolved from a niche methodology with ...

Applied Intuition announced Thursday it acquired EpiSci, the company whose software supported the Air Force's experimental X-62A VISTA last year in a dogfight with an F-16. (Richard Gonzales/Air Force ...

Abstract: Bayes' rule, although a powerful framework for performing state estimation, is often intractable for real-world, nonlinear dynamic systems. As a result, estimation algorithms typically rely ...

Patients were stratified to cohort A (unspecified tumors) or cohort B (rare genomic alterations). The TARGET-CRM design permits cohort B patients to immediately enroll at one dose level below the ...